Peregrine reports positive data from Cotara brain cancer trials

Mar 11, 2008 (Datamonitor via COMTEX) -- PPHM | news | PowerRating | PR Charts -- Peregrine Pharmaceuticals has presented positive results from two clinical trials assessing its targeted therapy Cotara, in the treatment of glioblastoma multiforme or GBM, a form of brain cancer.

The Cotara clinical update covers the first cohort of patients in its dosimetry trial as well as experience to date in an ongoing Phase II safety and efficacy trial. In patients treated in the studies, Cotara appears to be safe and well tolerated, with no dose-limiting adverse events. Patients who are continuing in the trials are being monitored for safety and overall survival, with several surpassing the median expected survival time for relapsed GBM patients.

Steven King, president and CEO of Peregrine, said: "In view of the short expected survival time of approximately six months in this patient population, it is promising that we have early GBM patients in these trials who have survived past the six-month timeframe, with one patient now surviving 15 months post-treatment."

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