A SOLICITATION OF THE NATIONAL INSTITUTES OF HEALTH AND THE CENTERS FOR DISEASE CONTROL AND PREVENTION FOR SMALL BUSINESS INNOVATION RESEARCH CONTRACT PROPOSALS

Jul 18, 2008 (FedBizOpps via COMTEX) -- SBCO | Quote | Chart | News | PowerRating -- NOTICE TYPE: Presolicitation Notice

DATE POSTED: 17-JUL-08

AGENCY: Department of Health and Human Services

OFFICE ADDRESS: OFFICE OF ACQUISITIONS6701 ROCKLEDGE DR RKL2/6100 MSC 7902 BETHESDA MD 20892-7902

SUBJECT: A Solicitation of the National Institutes of Health and the Centers for Disease Control and Prevention for Small Business Innovation Research Contract Proposals

CLASSIFICATION CODE: A - Research & Development

SOLICITATION NUMBER: PHS-2009-1

CONTACT: OFFICE OF EXTRAMURAL PROGRAMSOFFICE OF EXTRAMURAL RESEARCH, NATIONAL INSTITUTES OF HEALTH, PHONE 301-435-2688, EMAIL SBIR@OD.NIH.GOV

SETASIDE: N/A

NOTICE TEXT: Department of Health and Human Services National Institutes of Health NATIONAL HEART, LUNG AND BLOOD INSTITUTE, ROCKLEDGE DR. BETHESDA, MD A SOLICITATION OF THE NATIONAL INSTITUTES OF HEALTH (NIH) AND THE CENTERS FOR DISEASE CONTROL AND PREVENTION (CDC) FOR SMALL BUSINESS INNOVATION RESEARCH (SBIR) CONTRACT PROPOSALS 1. National Institutes of Health, Bethesda, MD 20892 and Centers for Disease Control and Prevention, Atlanta, GA 30305 are soliciting proposals from small business concerns that possess the research and development (R&D) expertise to conduct innovative research that will contribute toward meeting the program objectives of the agencies. A SOLICITATION OF THE NATIONAL INSTITUTES OF HEALTH (NIH) AND THE CENTERS FOR DISEASE CONTROL AND PREVENTION (CDC) FOR SMALL BUSINESS INNOVATION RESEARCH CONTRACT PROPOSALS [PHS 2009-1], with a closing date of November 3, 2008, for receipt of proposals, soon will be available electronically through the NIH Small Business Research Funding Opportunities (http://grants.nih.gov/grants/funding/sbir.htm) Web site. The SBIR Phase I Contract Solicitation will be available ONLY via electronic means. Printed copies of the Solicitation will not be distributed. Potential offerors are encouraged to check the NIH Small Business Research Funding Opportunities Web site for updates on the program. Any updates or corrections to the Solicitation will be posted there. The purposes of the SBIR program are to: (a) stimulate technological innovation; (b) use small business to meet Federal Research/Research & Development (R/R&D) needs; (c) foster and encourage participation by socially and economically disadvantaged small business concerns and by small business concerns that are 51 percent owned and controlled by women, in technological innovation; and (d) increase private sector commercialization of innovations derived from Federal R/R&D, thereby increasing competition, productivity and economic growth. For purposes of the SBIR program, a small business concern is any business concern that, on the date of award, (1) is organized for profit, with a place of business located in the United States, which operates primarily within the United States or which makes a significant contribution to the United States economy through payment of taxes or use of American products, materials or labor; (2) is in the legal form of an individual proprietorship, partnership, limited liability company, corporation, joint venture, association, trust or cooperative, except that where the form is a joint venture, there can be no more than 49 percent participation by foreign business entities in the joint venture; (3) is at least 51 percent owned and controlled by one or more individuals who are citizens of, or permanent resident aliens in, the United States; or is owned and controlled by another (one) small business concern that is itself at least 51 percent owned and controlled by one or more individuals who are citizens of, or permanent resident aliens in, the United States; AND (4) has, including its affiliates, no more than 500 employees. Following are the research topics identified in the NIH/CDC SBIR Contract Solicitation [PHS 2009-1]: NATIONAL INSTITUTES OF HEALTH (NIH) --NATIONAL CANCER INSTITUTE (NCI): Development of Molecular Pharmacodynamic Assays for Targeted Therapies; System to Analyze and Support Biomarker R&D Strategies; Development of Anticancer Agents; Innovative Methods for Manufacturing Safe, Effective Cancer Therapeutics; Biopsy Instruments and Devices that Preserve Molecular Profiles in Tumors; Innovative Strategies to Protect Radiosensitive Organs and Structures During Radiation Therapy; Quantitative Tissue Imaging For Clinical Diagnosis and Treatment; High Level Programming Language to Expedite Development of User Interfaces; Mobile Computing for Consumer-centered Cancer Prevention and Control; Health Information Technology to Facilitate Patient-centered Communication in Cancer-related Care; Antibody Array for Cancer Detection and Diagnosis; Novel and Improved Methods for Detecting Epigenetic Modifications; Development of shRNA Library Screening Technology for Cancer-Related Targets; Nanotechnology Imaging and Sensing Platforms for Improved Diagnosis of Cancer; Multifunctional Therapeutics Based on Nanotechnology; Novel Antibody Epitope Mapping Technologies; Protein Expression of Glycosylated Cancer Related Proteins; Peptide Aptamers: New Tools to Capture and Study Protein Interactions in Lieu of Immunological Reagents. NATIONAL CENTER FOR RESEARCH RESOURCES (NCRR): Visualizing Biomedical Research Characteristics. NATIONAL HEART, LUNG, AND BLOOD INSTITUTE (NHLBI): Ultrasonic Wave Transmitter, Transmission Line and Receiver for Interventional MRI; Nanoprobes for Non-Invasive Detection of Atherosclerotic Plaques; Development of Pathogen Inactivation Technologies for Blood Components; Development of Cell-based Bioassays Using Induced Pluripotent Stem (iPS) Cell Lines; Development of Novel Formulations for Iron Chelators to Treat Iron Overload in Patients on Transfusion Therapy; Multiplexed Assay Platforms for Protein Biomarkers of Cardiovascular Disease; Transcatheter Ablation Devices for Arrhythmia Treatment; Developing Novel Anticoagulants and Synthetic Heparins; Development of Gene Transfer Approaches for Correction of Genetic Blood Diseases; Wireless Communications Systems for Magnetic Resonance Imaging (MRI) Guided Surgery. NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM (NIAAA): Simple, Low-Cost, Onsite Biomarker Test Kits for Alcohol-Associated Disorders; Biological Sample Repository for Alcohol Research; Identification of miRNAs as Biomarkers for Alcohol-Induced Disorders. NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES: Clinical Sample Collection and Processing Technologies for Infectious Disease Diagnostics. NATIONAL INSTITUTE ON DRUG ABUSE (NIDA): Innovative Technologies to Support Economic Research in the Drug Abuse Treatment System; Instrument Development; Rapid Assessment Tools of Sexual and Drug Use Risk Behaviors; Electronic Drug Abuse Treatment Referral Systems for Physicians; Virtual Reality Simulations to Train Caregivers/Providers; Improvement of Reliability and Validity of Reporting of Sensitive Data; Development of Therapeutic Agents for Substance Use Disorders; Pharmaceutical Approaches for Development of Pharmacotherapies for Drug Addiction; Design and Synthesis of Treatment Agents for Drug Abuse; Repository for Substance Abuse Brain Imaging Data (SBIR/STTR); Web Based Cognitive/Neuropsychological Testing for Substance Abuse; Development Of Science Education Materials Or Programs; Screening, Characterization and Validation Assays for Protein Capture Reagents; Tool Development for New or Improved Capture Reagents. NATIONAL INSTITUTE OF MENTAL HEALTH (NIMH): Home-Based Lithium Level Testing for Bipolar Patients. CENTERS FOR DISEASE CONTROL AND PREVENTION (CDC) -- NATIONAL CENTER ON BIRTH DEFECTS AND DEVELOPMENTAL DISABILITIES (NCBDDD): Development of Web site with Modules for Study Participants and Fellow Researchers; Development of a Publication Database and Information Retrieval System with Announcement Feature; Development of Standardized Evaluation Software for Blood Disorder Public Health Surveillance Systems; Animated Software depicting Iron Out of Balance; Development and Evaluation of Web-based Applications Using Emerging Technologies and New Media; Application of Gaming Technology to Communicate Health Messages and Promote Healthy Living among Persons with Disabilities; Use of Cutting-edge Technology to Communicate with and Educate Health Care Professionals about Birth Defects, Developmental Disabilities, and Ways to Improve the Health and Wellness of Persons with Disabilities. NATIONAL CENTER FOR CHRONIC DISEASE PREVENTION AND HEALTH PROMOTION (NCCDPHP): Inexpensive, portable, user-friendly calibration of aneroid and electronic blood pressure devices; Dynamic Health Promotion Decision Making for Preconception Health and Healthcare; Development and Evaluation of a Quality and Affordable Electric-Assist Bicycle for Commuting. IMMUNIZATION SAFETY OFFICE (ISO): Novel or Enhanced Technology for Vaccination Delivery and Immunization Programs. 2. The NIH/CDC SBIR Contract Solicitation PHS 2009-1, including proposal forms, will be available electronically on/around August 8, 2008 through the NIH Small Business Research Funding Opportunities Web site. (Note: The PHS 2008-2 Omnibus Solicitation of the National Institutes of Health, Centers for Disease Control and Prevention, and Food and Drug Administration for Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) GRANT Applications, where investigator-initiated ideas are encouraged, is still open and is available at the same Web site noted above with remaining due dates of August 5 and December 5, 2008.) To understand better the differences between grants and contracts, see Contracts vs. Grants: What's the difference (http://grants.nih.gov/grants/funding/contracts_vs_grants.htm) LINKURL: http://grants.nih.gov/grants/funding/sbir.htm LINKDESC: National Institutes of Health Small Business (SBIR/STTR) Research Funding Opportunities. E-mail: sbir@od.nih.gov Point of contact Office of Extramural Programs, Office of Extramural Research, National Institutes of Health, Phone 301-435-2688, sbir@od.nih.gov.

INTERNET ADDRESS: https://www.fbo.gov/spg/HHS/NIH/NHLBI/PHS-2009-1/listing.html Provided by Federal Information & News Dispatch, Inc. (FIND) 202-429-5944

301-435-2688

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