From January 2005 to June 2008, an aggregate amount of 361160167 shares of VPHM have been shorted for a total dollar value of $4,333,922,004.00. The VPHM SqueezeTrigger price of $12.177 is the volume weighted average price that all shorts are short in shares of VPHM. There is still approximately $146,768,310.00 of potential short covering in shares of VPHM.
SqueezeTrigger.com has built a massive database that collects, analyzes and publishes a proprietary SqueezeTrigger Price for each stock that has been shorted. The data has then been integrated into an automated trading platform which can be used to connect to a live online broker and automate your trading of short squeeze events. It is extremely powerful with lightening fast execution at a very low price. Both the trading software and SqueezeTrigger data feed are available at http://www.squeezetrigger.com .
VIROPHARMA INC (NASDAQ:VPHM) ViroPharma Incorporated (ViroPharma), incorporated in September 1994, is a biopharmaceutical company dedicated to the development and commercialization of products that address serious diseases. The Company focuses on commercialization and development programs on products used by physician specialists or in hospital settings. ViroPharma has one marketed product and multiple product candidates in clinical development. It markets and sells Vancocin capsules hydrochloride (HCl), the oral capsule formulation of vancomycin hydrochloride, in the United States and its territories.
Vancocin is a potent antibiotic to treat antibiotic-associated pseudomembranous colitis caused by Clostridium difficile (C. difficile), and enterocolitis caused by Staphylococcus aureus (S. aureus), including methicillin-resistant strains. ViroPharma is developing maribavir for the treatment of cytomegalovirus (CMV), infection, and HCV-796 for the treatment of hepatitis C virus (HCV) infection. In November 2004, ViroPharma acquired all rights in the United States and its territories to manufacture, market and sell Vancocin, as well as rights to certain related vancomycin products, from Eli Lilly and Company (Lilly). Lilly retained its rights to Vancocin outside of the United States and its territories.
ViroPharma has three product development programs. It has two active programs that target: CMV with an initial focus on CMV infections in recipients of hematopoietic stem cell and bone marrow transplants and HCV. These programs are within the transplant and hospital settings or focus on diseases treated by hepatologists and gastroenterologists, and are at the center of the Company's strategic focus. The Company's third program has been licensed to Schering-Plough and targets picornaviruses with intranasal pleconaril.
As of December 31, 2005, ViroPharma had completed four Phase I clinical trials with maribavir to evaluate the potential for drug interactions and to evaluate the pharmacokinetics of maribavir in subjects with renal impairment and in subjects with hepatic impairment. A Phase II clinical trial with maribavir for the prevention of CMV infections in allogeneic stem cell transplant patients, which was initiated, during the year ended December 31, 2004, was enrolled as of November 2005.
In 2005, ViroPharma, with its partner Wyeth, completed a Phase I clinical trial with HCV-796 in healthy subjects. In November 2005, the Company announced the preliminary results of a Phase Ib proof of concept dose ranging clinical trial with HCV-796 in hepatitis C infected patients. Trial participants were given twice-daily administration of 50, 100, 250, 500, 1000, or 1500-milligram oral doses of HCV-796 or placebo for 14 days. The study assessed the safety, antiviral activity and pharmacokinetic profile of the drug compared to placebo. In this study, HCV-796 was generally well tolerated across the treatment groups, and no dose-limiting toxicity was identified. Mild to moderate headache was the most frequent adverse event reported overall. There were no treatment-emergent serious adverse events.
Pleconaril is a small molecule inhibitor of picornaviruses, which ViroPharma licensed from Sanofi-Aventis. In preclinical studies, pleconaril has demonstrated the ability to inhibit picornavirus replication in vitro by a novel, virus-specific mode of action. Pleconaril works by inhibiting the function of the viral protein coat, also known as the viral capsid, which is essential for virus infectivity and transmission. Preclinical studies have shown that pleconaril integrates within the picornavirus capsid at a specific site that is common to a majority of picornaviruses and disrupts several stages of the virus infection cycle.
The SqueezeTrigger database of approximately 1 billion short sale transactions goes back to January 1, 2005 and calculates the exact price at which the Total Short Interest is short in each stock. This data was never before available prior to January 1, 2005 because the Self Regulatory Organizations (primary exchanges) guarded it aggressively. After the SEC passed Regulation SHO, exchanges were forced to allow data processors like SqueezeTrigger.com to access the data. Total Short Interest is the number of shares shorted but not yet covered, and is different from total short volume. To access SqueezeTrigger Prices ahead of potential short squeezes beginning, visit http://www.squeezetrigger.com
About SQUEEZETRIGGER.COM
WWW.SQUEEZETRIGGER.COM is a service designed to help bonafide shareholders of publicly traded US companies fight short selling. SqueezeTrigger.com has built a proprietary database that uses Threshold list feeds and short sale time and sale data from NASDAQ, AMEX and NYSE to generate detailed and useful information to combat the short selling problem. For the first time, actual trade by trade data is available to the public that shows the attempted size, actual size, price and average value of short sales in stocks that have been shorted. This information is valuable in determining the precise point at which short sellers go out-of-the-money and start losing on their short trades.
SQUEEZETRIGGER.COM has built a massive database that collects, analyzes and publishes a proprietary SqueezeTrigger for each stock that has been shorted. The SqueezeTrigger database of nearly one billion short sale transactions goes back to January 1, 2005 and calculates the exact price at which the Total Short Interest is short in each stock. This data was never before available prior to January 1, 2005 because the Self Regulatory Organizations (primary exchanges) guarded it aggressively. After the SEC passed Regulation SHO, exchanges were forced to allow data processors like SqueezeTrigger.com to access the data.
The SqueezeTrigger database collects individual short trade data on over 7,000 NYSE, AMEX and NASDAQ stocks and general short trade data on nearly 8,000 OTCBB and PINKSHEET stocks. Each month the database grows by approximately 50,000,000 short sale transactions and provides investors with the knowledge necessary to time when to buy and sell stocks with outstanding short positions. By tracking the size and price of each month's short transactions, SQUEEZETRIGGER.COM provides institutions, traders, analysts, journalists and individual investors the exact price point where short sellers start losing money and a short squeeze can begin.
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