According to the company, the trial did not demonstrate an appreciable difference between patients treated with CERE-120 versus those in the control group. CERE-120 appeared to be safe and well tolerated.
CERE-120 is composed of an adeno-associated virus (AAV) vector carrying the gene for neurturin (NTN), a naturally occurring protein known to repair damaged and dying dopamine-secreting neurons, keeping them alive and restoring normal function. A Parkinson's disease is a progressive movement disorder and its main symptoms are caused by a reduction in dopamine containing nerve cells of the midbrain. Parkinson's patients exhibit a progressive inability to initiate and control physical movements.
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