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Human Genome Sciences, Inc. (NASDAQ: HGSI)
Human Genome Sciences, Inc. (NASDAQ: HGSI | Quote | Chart | News | PowerRating) closed yesterday down 1.81% on over 3.2 million shares traded.
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June 11, 2009 - Human Genome Sciences, Inc. (NASDAQ: HGSI | Quote | Chart | News | PowerRating) today announced the presentation of results from a long-term Phase 2 continuation trial showing that BENLYSTA(TM) (belimumab, formerly LymphoStat-B ) was associated with sustained improvement in disease activity across multiple clinical measures, decreased frequency of disease flares, and was generally well tolerated through four years on treatment in combination with standard of care in patients with serologically active systemic lupus erythematosus (SLE). The results were presented today in Copenhagen at the 2009 Congress of the European League Against Rheumatism (EULAR).
"Based on the results presented at EULAR 2009, the apparent durability of clinical effect and the favorable safety profile observed for belimumab suggest that belimumab has the potential to become an important new treatment for patients with SLE," said Joan T. Merrill, M.D., a study investigator, Program Chair, Clinical Pharmacology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, and Professor, Department of Medicine, University of Oklahoma Health Sciences Center.
About the company:
The mission of HGS is to apply great science and great medicine to bring innovative drugs to patients with unmet medical needs. The HGS clinical development pipeline includes novel drugs to treat hepatitis C, lupus, inhalation anthrax and cancer.
The Company's primary focus is rapid progress toward the commercialization of its two lead drugs, Albuferon (albinterferon alfa-2b) for hepatitis C and BENLYSTA(TM) (belimumab, formerly LymphoStat-B ) for lupus. Albuferon has now completed Phase 3 development, and the filing of global marketing applications is expected in fall 2009. Two Phase 3 trials of BENLYSTA are ongoing, with results expected in July and November 2009.
STAAR Surgical Company (NASDAQ: STAA)
STAAR Surgical Company (NASDAQ: STAA | Quote | Chart | News | PowerRating) closed yesterday down 5.70% on 371,300 shares traded.
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June 11, 2009 - STAAR Surgical Company, a leading developer, manufacturer and marketer of minimally invasive ophthalmic products, today announced that the FDA has granted 510(k) clearance for its Epiphany Injector System for use with the Affinity(TM) Collamer Three-Piece NTIOL and the Elastimide(TM) Silicone NTIOL. Introduction of the Epiphany will usher in a new era of insertion devices for the company and pave the way for the future introduction of a preloaded injector for the U.S. market.
STAAR named this product "Epiphany" based on the genesis of the product: the realization that the revolutionary proprietary technology used in our preloaded products outside of the U.S. could be modified and incorporated into a stand-alone injector for IOLs in other markets. Epiphany has been designed to combine both ease of use with controlled delivery. The Epiphany injector system is intended for single use and offers the flexibility of either twist or push insertion techniques - a unique feature of STAAR's IOL delivery systems.
About the company:
STAAR Surgical is a leader in the development, manufacture and marketing of minimally invasive ophthalmic products employing proprietary technologies. STAAR's products include the Visian ICL, a tiny, flexible lens implanted to correct refractive errors, as well as innovative products designed to improve patient outcomes for cataracts and glaucoma. Manufactured in Switzerland by STAAR, the ICL is approved by the FDA for use in treating myopia, has received CE Marking and is sold in more than 50 countries. Collamer is the brand name for STAAR's proprietary collagen copolymer lens material.
Metabasis Therapeutics, Inc. (NASDAQ: MBRX)
Metabasis Therapeutics, Inc. (NASDAQ: MBRX | Quote | Chart | News | PowerRating) closed yesterday up 15.79% on over 1.4 million shares traded.
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June 10, 2009 - Metabasis Therapeutics, Inc. announced yesterday that its four year research collaboration with Merck & Co., Inc. ("Merck"), focused on the discovery and development of AMP protein kinase (AMPK) activators, has yielded a lead candidate that Merck has selected to advance into late preclinical development. In addition, under an amended agreement, Merck has agreed to pay Metabasis a one-time fee of $6 million that satisfies all future obligations for milestones and royalty payments.
Metabasis and Merck entered into a collaboration and license agreement in June 2005 focused on the discovery, development and commercialization of AMPK activators for the treatment of various metabolic diseases. As part of the original agreement, Metabasis received funding for a three year research term, which was extended by another year, through June 2009. Also in the original agreement, Metabasis received an upfront payment of $5 million, funding for its research contribution to the program, and was eligible to receive payments upon achievement of certain milestones associated with the development of a product candidate, as well as a royalty on net sales should a product be commercialized.
About the company:
Metabasis is a biopharmaceutical company that has established a broad pipeline of product candidates and advanced discovery programs targeting large markets with significant unmet needs. The Company's product pipeline includes clinical-stage product candidates and advanced discovery programs for the treatment of metabolic diseases such as diabetes and hyperlipidemia, as well as product candidates and advanced discovery programs for the treatment of liver diseases such as hepatitis and primary liver cancer.
Level 3 Communications, Inc. (NASDAQ: LVLT)
Level 3 Communications, Inc. (NASDAQ: LVLT | Quote | Chart | News | PowerRating) closed yesterday up 17.70% on over 62.2 million shares traded.
To view the complete release, please visit: http://wallstreetnewsalert.com/fullstory.php?id=1270
June 11, 2009 - Level 3 Communications, Inc. (NASDAQ: LVLT | Quote | Chart | News | PowerRating) today announced that it is extending and expanding its relationship with First Commercial Bank of Florida (FCB), which provides personal and commercial banking services to customers in central Florida.
Under the terms of the agreement, Level 3 will continue to deliver primary Internet connectivity to the nine bank branches and the company's operations center and will provide primary 'and redundant data storage. As part of the contract, Level 3 will augment the services it already delivers to include an IP-based virtual private network connecting all of the company's 10 locations.
About the company:
Level 3 Communications, Inc. is a leading international provider of fiber-based communications services. Enterprise, content, wholesale and government customers rely on Level 3 to deliver services with an industry-leading combination of scalability and value over an end-to-end fiber network. Level 3 offers a portfolio of metro and long-haul services, including transport, data, Internet, content delivery and voice.
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