By offering Risperdal in a more convenient biweekly injectable form as opposed to a daily oral preparation, the company aims to fend off competition from generic versions.
Risperdal is Janssen Pharmaceutical's leading product, accounting for some 30 per cent of the company's total sales in 2008. But sales in 2008 totaled only 29.5 billion yen (US$302 million), compared with the 34.5 billion yen in 2007, because the product had to vie with generic versions.
Janssen already sells Risperdal in the form of pills, granules, liquid and quick-dissolving tablets. But these need to be taken twice a day, so people suffering from schizophrenia have difficulty staying on their medication.
The new injectable form of Risperdal, to be sold as Risperdal Consta, is formulated in tiny beads of a slow-release polymer that is injected into the muscle, where it gradually dissolves over the course of two weeks.
Risperdal Consta is already being sold overseas. But for the Japanese market, Janssen Pharmaceutical halved the size of the packaging so the product takes up less room in the small refrigerators found in Japanese hospitals. The company obtained approval to market the formulation from the Health Ministry in April.
(Nikkei)

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