The current program becomes the second HuCAL antibody derived from MorphoSys's collaboration with Centocor Ortho Biotech to enter the clinic.
In 2007, Centocor Ortho Biotech started a Phase I study with a HuCAL antibody in oncology patients and commenced a Phase II trial in an immunological indication using the same antibody one year later. The antibody became the first from MorphoSys to be developed in two different indications. With the new study, Centocor Ortho Biotech will be running three clinical trials of HuCAL antibodies.
MorphoSys anticipates that in 2009, between two and four partnered programs will enter clinical trials. Altogether, the partnered and proprietary pipeline of MorphoSys is expected to comprise up to eight compounds in clinical trials by the end of 2009, with at least three antibodies in Phase II.
Simon Moroney, CEO of MorphoSys, said: "The advancement of a new HuCAL antibody into human clinical trials is an important step forward for MorphoSys. Progress in the development of innovative biopharmaceutical agents by our partners is a key driver of our company's growth."
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