GE Healthcare and Geron sign stem cell agreement

Tue. June 30, 2009; Posted: 09:36 AM

Jun 30, 2009 (Datamonitor via COMTEX) -- GE | Quote | Chart | News | PowerRating -- GE Healthcare, a unit of General Electric Company, and Geron, a biotechnology company, have entered into a global exclusive licensing and alliance agreement to develop and commercialize cellular assay products derived from human embryonic stem cells for use in drug discovery, development and toxicity screening. Financial terms were not disclosed.

Under the terms of the agreement, GE Healthcare has been granted an exclusive license under Geron's intellectual property portfolio covering the growth and differentiation of human embryonic stem cells (hESCs), as well as a sublicense under Geron's rights to the foundational hESC patents held by the Wisconsin Alumni Research Foundation.

GE Healthcare and Geron have established a multi-year alliance program under which scientists from the two companies will work closely together to develop hESC-based products for drug discovery. The program will use stem cells derived from hESC lines listed on the NIH Human Pluripotent Stem Cell Registry. GE Healthcare will fund the R&D program and will be responsible for manufacturing, sales and distribution of products developed under the agreement.

The GE Healthcare-Geron alliance aims to develop cellular assay products derived from hESCs that could be used in early in vitro screening of drug candidates. Under the terms of the agreement, intellectual property rights arising from the alliance program research will be shared, with GE Healthcare receiving rights for the development of drug discovery technologies, and Geron receiving rights for cell therapy applications.

The combination of GE Healthcare's Cell Factory capability for cell reproduction and manufacturing with Geron's hESC technology will make it possible to generate a large scale supply of hESC-derived cells which retain normal cellular functions and could address bottlenecks in new drug research and accelerate the drug development process, the companies said. The first products developed in the GE Healthcare and Geron alliance are expected to be available by early 2010, with a pipeline of products to follow.

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