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Inovio forms collaboration for development of influenza vaccine

Posted on: Tue, 30 Jun 2009 09:36:00 EDT

Symbols: INO

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Jun 30, 2009 (Datamonitor via COMTEX) --
INO | Quote | Chart | News | PowerRating -- Inovio Biomedical, a late stage biomedical company, has established a new collaboration with the National Microbiology Laboratory of the Public Health Agency of Canada and the University of Pennsylvania to further evaluate the company's DNA vaccine candidates against swine influenza A virus.

As a part of its universal influenza vaccine program, Inovio has designed and manufactured consensus DNA vaccines for H1N1 influenza strains. These consensus vaccines, delivered using Inovio's proprietary electroporation technology, have the potential to provide protection against a broad scope of existing as well as currently unknown, unmatched influenza strains that could emerge - one of the perpetual challenges in trying to protect against influenza, the company said.

The purpose of this collaboration is to test these vaccine candidates against pandemic and seasonal influenza strains in animal models and will include testing against a recently identified swine H1N1 strain.

Inovio's influenza vaccine constructs were designed using the company's novel SynCon technology, which facilitates the design of DNA-based vaccines capable of protecting against unmatched sub-types and strains of pathogens.

Joseph Kim, Inovio's CEO, said: "The current swine flu outbreak highlights the fact that the world cannot rely solely on the 'catch-up' strategy of influenza vaccine design. We need vaccines that provide at least some broad protective capability against evolving seasonal influenza strains and those with pandemic potential.

"We have already achieved significant validating data in large animal models regarding the ability of Inovio's consensus vaccines to protect against unmatched strains of different influenza sub-types and look forward to the data resulting from this collaboration of vaccine experts."

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