The Phase II randomized, placebo-controlled trial is designed to investigate whether therapeutic immunization during highly active antiretroviral therapy induces elevations of HIV-specific T cell precursors with high proliferative capacity (PHPC) in HIV-1-infected individuals, and whether the quantity of PHPC correlates with the viral load set point following analytical treatment interruption.
This second Phase II study is conducted at the IRCCS Policlinico S Matteo in Pavia, Italy with a total of 16 patients.
Julianna Lisziewicz, CEO of Genetic Immunity, said: "We are extremely pleased to have enrolled all patients in this, our second Phase II trial aimed to prove the benefit of our immune amplification therapy. We now have two trials underway, in addition to a Phase I/II trial that is also nearing completion. I am confident this Italian trial, along with the one conducted in Hamburg, Germany will show substantial benefit for HIV infected patients. We look forward to receiving trial data once it is completed early in 2010."
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