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The deal focuses on Hydra's R&D program for ion channel compounds that target the TRPA1 receptor, which is believed to have an important role in pain management.
Under the terms of the agreement, Hydra receives an upfront payment of $5 million from Cubist. The agreement allows for Cubist to support Hydra's internal development on the TRPA1 program by providing $5 million in R&D funding per year for two years, with an option to renew.
The joint development program will build on the existing R&D base of Hydra's TRPA1 compounds, preclinical data, and pharmacology studies. As the collaboration progresses into potential future stages, Hydra is eligible for potential development milestones and royalties on products produced from the joint program. The goal of the program is to identify TRPA1 drug candidates for use as acute care therapeutics for the management of pain.
Russell Herndon, CEO of Hydra Biosciences, said: "We are pleased to collaborate with Cubist and to advance innovative drug candidates using our ion channel platform. While our platform has potentially broad applications in the treatment of pain, inflammation, cardiovascular and other diseases, this collaboration is a step forward in advancing our pipeline for novel ion channel drugs for pain management."
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