Medicines Company wins CHMP positive opinion for Angiox

Mon. October 26, 2009; Posted: 12:27 PM

Oct 26, 2009 (Datamonitor via COMTEX) -- MDCO | Quote | Chart | News | PowerRating -- The Medicines Company, a US-based pharmaceutical company, has reported that the Committee for Medicinal Products for Human Use or CHMP has granted a positive opinion applicable to all member states of the EU/European Economic Area that will extend the use of Angiox to include patients with heart attacks undergoing emergency heart procedures called primary percutaneous coronary intervention.

The basis of this approval is the Horizons-AMI study which was the first drug trial to demonstrate a reduction in deaths from heart attacks in patients undergoing emergency percutaneous coronary intervention (PCI).

The trial showed that patients treated with Angiox compared with today's leading treatment - heparin plus a platelet glycoprotein IIb/IIIa (GPI) inhibitor - were more likely to survive and had less frequent severe bleeds.

Gilles Montalescot, professor of the Pitie-Salpetriere Hopital, France, said: "The HorizonsAMI trial confirms the role of Angiox as an alternative anticoagulant strategy to treat patients with acute myocardial infarction undergoing primary PCI.

"The safety benefit observed with bivalirudin against unfractionated heparin + GPIIb/IIIa inhibitors is a real contribution to interventional cardiology in the contemporary era of evidence based medicine."

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For full details on Medicines Company The (MDCO) click here. Medicines Company The (MDCO) has Short Term PowerRatings of 4. Details on Medicines Company The (MDCO) Short Term PowerRatings is available at This Link.

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