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AMT has developed Glybera as a gene therapy for patients with this disease and had announced new clinical data showing that a one-time administration of Glybera results in significant long-term health benefits for LPLD patients.
Long-term follow-up data from two clinical trials with complete LPLD patients show that Glybera therapy results in a significant and clinically important reduction in acute pancreatitis, the most debilitating complication of the disease. The data also confirm that the therapy is well-tolerated and safe.
AMT intends to file Glybera for marketing approval with EMEA by the end of this year.
LPLchip, based on the Progenika's DNA-chip technology, will be used to rapidly diagnose patients with complete and partial LPLD and will be important to effectively identify patients that could benefit from Glybera.
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