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Merck Eprova signs license agreement with Isofol Medical for Modufolin(R)

Posted on: Thu, 12 Nov 2009 13:35:00 EST

Symbols: MRK, MKGAY

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Nov 12, 2009 (Datamonitor Financial Deals Tracker via COMTEX) --
MKGAY | Quote | Chart | News | PowerRating -- Merck Eprova AG has signed an exclusive license agreement with Isofol Medical AB, a Sweden-based developer of new method for the treatment of cancer, to utilize Merck Eprova's proprietary folate compound Modufolin(R) in oncology. Merck Eprova is a Switzerland-based wholly-owned subsidiary of Merck KGaA, a Germany-based pharmaceutical and chemicals company.

Under the terms of the agreement, Merck Eprova will provide Modufolin(R), the active metabolite of LV (Leucovorin), for use in clinical trials and commercial drug products.

Modufolin is a biomodulator originally designed to replace LV as the preferred folate to enhance the activity and reduce associated toxicity of 5-FU (5-fluorouracil), a widely used anti-cancer drug. Isofol Medical will conduct phase I and II studies using a combination of Modufolin and antifolates starting in autumn 2009 and expected to close by the end of 2010.

Deal Type    Partnership
Sub-Category Acquisition of Rights
Deal Status  Announced: 2009-11-11

Deal Participants

Partner 1 (Company) Merck Eprova AG
Partner 2 (Company) Merck KGaA
Partner 3 (Company) Isofol Medical AB

For full details on Merck & Co (MRK) MRK. Merck & Co (MRK) has Short Term PowerRatings at TradingMarkets. Details on Merck & Co (MRK) Short Term PowerRatings is available at This Link.

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